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MEGLUMINE(N-Methyl-d-glucamine)

MEGLUMINE(N-Methyl-d-glucamine)
Product Detailed
Related Categories:Pharmaceutical
USP27 TOP GRADE
MEGLUMINE

PRODUCT IDENTIFICATION

CAS NO.6284-40-8
EINECS NO.228-506-9
FORMULACH3NHCH2(CHOH)4CH2OH
MOL WT.195.22

H.S. CODE

2922.19

TOXICITY

SYNONYMS1-Deoxy-1-methylaminosorbitol; N-Methyl-d-glucamine;
DERIVATION

CLASSIFICATION

 

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATEwhite powder
MELTING POINT 128 - 132 C
BOILING POINT 
SPECIFIC GRAVITY  
SOLUBILITY IN WATER 
pH 
VAPOR DENSITY 

AUTOIGNITION

350 C

NFPA RATINGS

Health: 0; Flammability: 0; Reactivity: 1

REFRACTIVE INDEX

 
FLASH POINT 
STABILITY

Stable under ordinary conditions

GENERAL DESCRIPTION AND APPLICATIONS

Glucamine, 1-amino-1-deoxy-D-sorbitol, is an amine formed by reduction of glucosylamine or  glucose oxime. N-alkylated glucamines are prepared from D-glucose and relevant alkylamines. Meglumine is N-methyl glucamine, a derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. It is a white crystalline powder; melting at 130 C. Meglumine is used in the preparation of certain radiopaque media such as diatrizoate meglumine and iodipamide meglumine. Meglumine is combined as an excipient (an inert substance) not an active ingredient. Excipients are added to ensure that the shelf-life of the active ingredients can be long enough to be active until internal use. Excipients are combined also to support the active ingredients, so that the latter can be easily administered or absorbed in the body. Examples of meglumine-combined drugs are flunixin meglumine (non-steroidal anti-inflammatory drugs, used as a veterinary anti-inflammatory and analgesic) and meglumine antimoniate (antiprotozoal to treat leishmaniasis). Meglumine is used in ion-exchange resins to chelate boron ions selectively. N-alkyl glucamines are used in preparing functional surfactants and some solutions which are stable over a wide range of pH and ionic strength.
SALES SPECIFICATION

APPEARANCE

white powder

ASSAY

99.0% min

OPTICAL ROTATION

-15.5° ~ -17.5°

LOSS ON DRYING

0.5% max

TRANSPORTATION
PACKING25kgs in fiber drum
HAZARD CLASS 
UN NO. 
OTHER INFORMATION
Hazard Symbols: , Risk Phrases: , Safety Phrases: 24/25

MEGLUMINE(N-Methyl-d-glucamine)



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